At CapeRay we are working feverishly to complete the laboratory testing of our dual-modality Aceso system prior to initiating a clinical trial later this month. The breast-imaging device incorporates a pair of remote-controlled foot pedals that the radiographer uses to control the vertical movement of the imaging platform and compression paddle. Our industrial designer, John Harverson, utilized SolidWorks, a sophisticated computer-aided design package to create a 3D prototype that formed the “positive” for a silicone mould. The resulting foot pedals are an elegant feature of our user interface (see image at right).
The real revolution in 3D printing of medical devices is taking place in the field of implants. Because the technology enables different anatomical shapes to be accommodated, a variety of prototypes have been printed: ears; heart valves; bones; blood vessels; and skin grafts. The challenge, however, is to create a prosthesis using fabrication materials that are biocompatible.
A biomedical engineer from North Carolina, Roger Narayan, has just published a paper in Regenerative Medicine in which he and his colleagues described the incorporation of a naturally occurring compound into a 3D printing process to create a medical implant. The compound was riboflavin, better known as vitamin B2 and found in everything from asparagus to eggs.
The team utilized two-photon polymerization, a process in which the precursor liquid materials are solidified when exposed to light, enabling the creation of small objects with detailed features — such as scaffolds for tissue engineering (see image above left) and implantable drug-delivery devices. The major benefit of riboflavin, which is mixed with the precursor materials to make them photoreactive, is that it is both nontoxic and biocompatible, unlike most other chemicals used in two-photon polymerization. Narayan enthused, “This opens the door to a much wider range of biocompatible implant materials, which can be used to develop customized implant designs using 3D printing technology.”